MEMBERS COUNT : 1863


How Coronavirus kills its victims

July 1, 2020

 1790     1627

This essay has two apparently contradictory messages. On the one hand, it affirms that the coronavirus disease, otherwise known as COVID-19, is not necessarily a death sentence.

There are countries, such as Uganda and Vietnam, which have recorded no deaths so far, despite confirmed cases of coronavirus.

Although over 500 deaths have been recorded in Nigeria, nearly double that number has recovered from the disease. But that is only one side of the story.

On the other hand, the coronavirus disease is a death bomb for certain individuals who are infected. That’s why over half a billion people so far have died of the virus worldwide.

True, people with pre-existing conditions, such as heart, lung, or kidney disease, are at greater risk of death, the data so far show that the virus can kill just about anybody.

Yet, there is neither a certified cure nor a vaccine against the virus as of today.

In the search for cure or vaccine, researchers have studied the behaviour of the virus in the last six months, while others have studied selected autopsies of dead victims, in order to understand why so many people have died of the virus. Such knowledge is necessary in order to develop an effective cure or vaccine.

Three findings stand out. First, there is no doubt that the coronavirus is capable of laying its victims to waste as it can cause massive devastation of various organs.

When the virus enters through the mouth, nose, or eyes, its first home is the upper respiratory tract. The virus binds to particular receptors and begin to replicate itself.

The receptors, technically known as Ace-2, help in regulating blood pressure. They are common in the upper respiratory tract but are also found in the lungs, heart, kidney, intestine, blood vessels, and even the brain.

Research shows that the virus may migrate from this initial binding to the receptors in the other organs listed above.

The presence of the virus in these receptors, especially those in the blood lining, may be the reason for the unusually excessive clotting of the blood and why patients with hypertension and diabetes are at very high risk.

Worse still, Ace-2 receptors may help the virus reach as far as the brain, where it binds to the Ace-2 receptors in the brain.

This may well explain some of the bizzare symptoms of the virus, such as loss of taste and smell, erratic breathing, irregular heartbeat, seizures, stroke, and even nervous breakdown.

Second, it has been found that it is not the virus alone, which kills its victims. The body’s defence mechanism deployed in fighting the virus can overreact and cause death.

Here, in a nutshell, is how it happens. When a pathogen (virus, bacterium, or any other microorganism) enters the body, immune cells are attracted to the point of infection to destroy the intruder.

A protein, technically known as cytokine, is released by the body to coordinate the body’s response to the intruder.

In the process, excess white blood cells are produced, which rush to the point of infection to fight it. Inflammation follows as part of the process of healing the body from the infection.

Unfortunately, however, the body’s immune system can overreact, leading to a “cytokine storm”, whereby excess immune cells are produced, leading to hyper-inflammation.

In the process, the body is destroyed along with the virus. The patient may get better and even test negative for the virus, while still in hospital.

However, multiple organs may have been destroyed and blood pressure may drop to dangerous levels. When a patient gets to this level, death often follows.

A third major finding helps to explain why individuals vary in their reaction to coronavirus infection, that is, why some die while others survive, even in old age.

First, although humans share the same genes, the ways in which the genes are regulated in the body differ from person to person.

Therefore, many victims of coronavirus may weather the storm and survive the infection, while others succumb to it, depending on their genetic makeup.

Genetic variation may also explain why Ace-2 receptors are expressed differently in different organ tissues, depending on the individual.

As indicated earlier, the underlying condition of the various organs is also a critical factor. That’s why those with preexisting conditions are at much greater risk.

However, as the above findings and the data on coronavirus deaths show, there have been people with no preexisting condition, who nevertheless still died of the virus. Not just old people, but young folks as well.

It is natural for readers of this essay to ask: What’s the treatment or what’s the best treatment? The simple truth is that, as of today, there is no cure for coronavirus.

Each case is often managed as it comes and as the patient’s condition deteriorates. This is not to say that there are no treatment options.

The naked truth is that no option has been found to completely prevent death in all patients or even in the majority of patients.

That leaves you and me with the non-pharmaceutical option of following the WHO-sanctioned guidelines, provided by the Nigeria Centre for Disease Control and echoed repeatedly by the Presidential Task Force on COVID 19:

    Stay at home, if you are not working or on essential service.
    Wear face masks, if you go out. You should even wear one at home, if you are coughing or sneezing or if someone in your household is.
    Maintain physical distancing of at least six feet (ese bata mefa) whenever you go out.
    Avoid touching your mouth, nose, or eyes.
    Wash your hands frequently with soap or alcohol-based sanitizer.
    Main good overall hygiene at all times, including occasionally wiping door handles, remote controls, and your phones, with disinfectant.

In addition, the oga among us must ensure that their aides, drivers, cooks, gardeners, and other dependents or co-workers follow these guidelines.

They must work with leaders in their primary or secondary communities to educate people about the existence and prevalence of this virus and to let them know that it can kill.

For now, following these mitigation measures is our best bet. To put it in another way, the best cure for coronavirus for now is NOT to catch the disease at all.



Comments

Post by chidi60 on 05 August 2020, 10:47 am

Nice update


Post by Ebex on 04 August 2020, 21:02 pm

Covid 19


Post by Bishop49 on 04 August 2020, 19:09 pm

Nice


Post by Omosuvie on 04 August 2020, 16:36 pm

Ok


Post by chidi60 on 04 August 2020, 11:23 am

Thanks for the update


Post by Nonelikegod on 04 August 2020, 09:05 am

Thanks


Post by Kayjee2 on 04 August 2020, 05:27 am

Thanks for the information


Post by Michael234 on 04 August 2020, 02:26 am

hgd


Post by Bishop49 on 03 August 2020, 16:31 pm

Ok


Post by Waripamowei001 on 03 August 2020, 15:26 pm

OK


Post by Chidom Igwe on 03 August 2020, 12:59 pm

Okay


Post by Kayjee2 on 03 August 2020, 10:18 am

Thanks for the information


Post by Michael234 on 03 August 2020, 09:22 am

ok


Post by Sherifffamosa on 03 August 2020, 08:40 am

Noted


Post by Nonelikegod on 03 August 2020, 07:52 am

Okay


Post by Annie on 03 August 2020, 06:37 am

Good


Post by Chidom Igwe on 02 August 2020, 23:14 pm

Okay


Post by Santiagojr on 02 August 2020, 13:01 pm

Okay


Post by Michael234 on 02 August 2020, 12:09 pm

ok


Post by Bishop49 on 02 August 2020, 09:20 am

Ok


Post by Nonelikegod on 02 August 2020, 08:19 am

Good one


Post by Kayjee2 on 02 August 2020, 08:01 am

Covid 19 is real2


Post by Ebex on 02 August 2020, 06:27 am

Covid 19


Post by Bishop49 on 01 August 2020, 20:21 pm

Ok


Post by Ebex on 01 August 2020, 19:23 pm

Too bad


Post by Kayjee2 on 01 August 2020, 09:56 am

That good


Post by Nonelikegod on 01 August 2020, 07:01 am

Its okay


Post by Chidom Igwe on 01 August 2020, 05:27 am

Okay


Post by richguy2224 on 31 July 2020, 16:02 pm

Good


Post by Michael234 on 31 July 2020, 11:14 am

Ok


Post by Nonelikegod on 31 July 2020, 08:10 am

Nice one


Post by chidi60 on 31 July 2020, 07:47 am

Nice information


Post by Kayjee2 on 31 July 2020, 06:29 am

Nice information


Post by Habeeb878 on 30 July 2020, 23:58 pm

Ok


Post by Chidom Igwe on 30 July 2020, 23:29 pm

God will see us through


Post by Tabitha080 on 30 July 2020, 20:17 pm

Nice information


Post by Sylva_Uk on 30 July 2020, 18:37 pm

Ok


Post by Sammy42 on 30 July 2020, 13:30 pm

For now, following these mitigation measures is our best bet. To put it in another way, the best cure for coronavirus for now is NOT to catch the disease at all.


Post by Adewesco on 30 July 2020, 10:55 am

Ok


Post by Mustinaas on 30 July 2020, 09:50 am

Nice information


Post by Calebite on 30 July 2020, 08:27 am

OK


Post by Kayjee2 on 30 July 2020, 07:58 am

Nice information from Giftalworld


Post by Odinakaesther1 on 30 July 2020, 07:05 am

Okay


Post by Nonelikegod on 30 July 2020, 06:54 am

Very good


Post by Kitara4363 on 30 July 2020, 06:49 am

Ok


Post by Calimay on 30 July 2020, 06:31 am

Nice information from Giftalworld, although no longer recent


Post by Ebex on 30 July 2020, 04:50 am

Hmm


Post by Nate2002 on 30 July 2020, 00:27 am

Thats very sad


Post by Michael234 on 30 July 2020, 00:09 am

Ok


Post by Santiagojr on 29 July 2020, 23:43 pm

Okay


Post by Phardoswiz on 29 July 2020, 23:02 pm

Thanks for the update


Post by Chriszubby on 29 July 2020, 21:21 pm

Thanks for the update


Post by Callista on 29 July 2020, 20:38 pm

Nice


Post by Chijioke5 on 29 July 2020, 20:27 pm

It's alright


Post by Bartholomew on 29 July 2020, 20:00 pm

Ok


Post by Ikechukwu on 29 July 2020, 19:37 pm

Ok


Post by Chidom Igwe on 29 July 2020, 17:19 pm

Fine one


Post by Calimay on 29 July 2020, 16:43 pm

Thanks to GIFTALWORLD for the information contained in this post


Post by Daniel2020 on 29 July 2020, 16:29 pm

Well done


Post by Tonye T on 29 July 2020, 15:47 pm

Ok


Post by Jose2 on 29 July 2020, 15:40 pm

Ok


Post by Franchika on 29 July 2020, 14:50 pm

Nice update


Post by Bitrus danjuma on 29 July 2020, 12:02 pm

Good


Post by Sammie on 29 July 2020, 10:16 am

Nice information


Post by Nonelikegod on 29 July 2020, 09:14 am

Nice one


Post by Slimgold20 on 29 July 2020, 08:42 am

Thanks


Post by Slimgold20 on 29 July 2020, 08:42 am

Thanks


Post by chidi60 on 29 July 2020, 08:28 am

Ok


Post by Jeffpallo on 29 July 2020, 08:08 am

ok


Post by Adewesco on 29 July 2020, 06:48 am

Ok


Post by MAMUS ONOS on 29 July 2020, 06:44 am

God save us all


Post by youngfellow on 29 July 2020, 06:37 am

Nice update


Post by Kayjee2 on 29 July 2020, 06:10 am

Good and nice upgrade


Post by Ecko on 29 July 2020, 04:26 am

Very Bad


Post by Marvel on 29 July 2020, 04:18 am

Thanks for the update


Post by Ebex on 29 July 2020, 03:22 am

This is deadly


Post by Michael234 on 29 July 2020, 00:15 am

ok


Post by Abbarukkaiya on 28 July 2020, 23:16 pm

Thanks for the update


Post by mustaphatg on 28 July 2020, 22:58 pm

ok


Post by Ikechukwu on 28 July 2020, 21:53 pm

So cute


Post by Gero on 28 July 2020, 21:21 pm

ok


Post by Genius on 28 July 2020, 21:17 pm

Good one there


Post by Chriszubby on 28 July 2020, 21:03 pm

Ok


Post by Salay on 28 July 2020, 20:46 pm

Okay


Post by Bartholomew on 28 July 2020, 20:18 pm

Ok


Post by Bartholomew on 28 July 2020, 20:18 pm

Ok


Post by Udybliss1 on 28 July 2020, 20:03 pm

Okay


Post by Callista on 28 July 2020, 19:26 pm

Ok


Post by ELVIS on 28 July 2020, 19:02 pm

Great